Recommend 1st Disk Drive Protector 3.0

Protect your PC from abusive use of removable media and enforce whether your users are allowed to use removable media or access your local drives. This software lets you hide, lock and prevent usage of local, network, Floppy and USB drives as well as disable the AutoRun feature for them. If you hide and lock all the drive letters you do not normally use, you will prevent any inserted removable media from appearing and being accessible in My Compu